Evaluation the relation between age at the time of diabetes diagnosis and Glutamic acid decarboxylase (GAD) antibody in non- overweight, obese diabetic individuals

Ngôn ngữ sử dụng

Cách trích dẫn

Tran, T. N. (2021). Evaluation the relation between age at the time of diabetes diagnosis and Glutamic acid decarboxylase (GAD) antibody in non- overweight, obese diabetic individuals. Vietnam Journal of Diabetes and Endocrinology, (40), 39-44. https://doi.org/10.47122/vjde.2020.40.7

Tóm tắt

Objective: Evaluation the relation between age at the time of diabetes diagnosis and glutamic acid decarboxylase (GAD) antibody in non- overweight, obese diabetic individuals. Method: A cross-sectional study on 284 non overweight- obesity diabetic patients at Hue Central hospital from August 2017 to August 2019. All patients were measured autoantibodies glutamic acid decarboxylase (anti-GAD). GAD antibody- positive was determined when autoantibodies to GAD concentration was higher than 5 IU/mL. Clinical data (age, sex, weight, hight) were obtained. Age at the time of diabetes diagnosis was interviewed. Data were analysed by SPSS version 16.0 and Medcalc software. Results: The risk of glutamic acid decarboxylase (GAD) antibody- positive in non- overweight, obese diabetic individuals increased 2.7 time when aged at the time of diabetes diagnosis 50 and older. The cut-off of age at the time of diabetes diagnosis for detecting risk of glutamic acid decarboxylase (GAD) antibody- positive in non- overweight, obese diabetic individuals was 57. Conclusion: This study showed non- overweight, obese diabetic individuals should be screened for glutamic acid decarboxylase (GAD) antibody at aged 50 and older

https://doi.org/10.47122/vjde.2020.40.7