Background: Health-related quality of life is one of the most widely-used measures to self-assess the effect of the management of chronic disease on health, and monitors the physical, psychological and social aspects of personal health. These data in elderly diabetic Vietnamese is currently limited. Objectives: To measure health-related quality of life in elderly diabetic patients at Ha Dong Traditional Medicine Hospital. Methods: A cross-sectional study was performed in 107 patients aged 60 years or older, who was examined and treated at the Ha Dong Traditional Medicine Hospital. The subjects were interviewed by a designed questionnaire. Health-related quality of life was measured using SF-36 questionnaire. Results: Among 107 participants, the mean age was 66.1 ± 6.4 years; women account for 66.4%. The average duration of diabetes was 9.6 ± 5.0 (years). The percentage of patients with blood glucose control and HbA1c reaching their targets is 44.9% and 62.6%, respectively. The mean number of complications was 1.3 ± 0.7. Average quality of life score of study subjects was: 43.49 ± 9.30. Average score of mental health (49.32 ± 8.58) which was higher than physical health (37.85 ± 10.93) indicates that the patient has a quality of life related to mental health better than physical health. Conclusion: The quality of life for diabetic elderly patients at Ha Dong Traditional Medicine Hospital was not good, especially the quality of life related to physical health. Good control of blood glucose, prevention and treatment of comorbidities and minimizing complications of diabetes help improve the quality of life for patients.