Abstract

Lactic acidosis is an accumulation of too much lactic acid in the blood, a common metabolic acidosis, especially in severe cases, when lactic acidosis is a complication of main disease. In clinical practice, people are divided into 2 types: Lactic acidosis type A is often caused by lack of oxygen in the tissue, type B is caused by the combination with other diseases. Lactic acidosis typically occurs due to glucose metabolism in the absence of tissue oxygenation or by the liver's inability to remove lactic acid. Severe acidosis can reduce the contractile force of the heart, increase pulmonary vascular resistance, increase myocardial sensitivity to arrhythmia, increase blood potassium, inhibit metabolism in cells or at molecular level. Mortality is high, from 40-60% of cases