Abstract
Objective: To evaluate some of clinical characteristics and glutamic acid decarboxylase (GAD) antibody levels in non- overweight/obese patients with diabetes. Method: A cross-sectional study on 284 non overweight/obesediabetic patients at Hue Central Hospital from August, 2017 to August, 2019. All patients were measured autoantibodies glutamic acid decarboxylase (anti-GAD). GAD antibody- positive was determined when autoantibodies to GAD concentration was higher than 5 IU/mL. Clinical data (age, sex, weight, hight) were obtained. Data were analysed by SPSS version 16.0. Results: In non overweight/obese diabetic patients with GAD antibody- positive, the average age was 60.27 ± 16.57 year, lower than in GAD antibody- negative patients group (66.86 ±14.32 year), p<0.05. In diabetic patient group with GAD- antibody positive , women accounted for 40.91% and men accounted for 59.09%. The percentage of GAD-antibody positive in patients aged 35 years and older were distributed as follows: aged 40 and younger: 16.67%; ages 40 to 59: 11.11%; ages 60 to 74: 7.44%; and aged 75 and older: 4.4%; Conclusion: In non overweight/obese diabetic patients, GAD-antibody positive condition is descending with age