Tóm tắt

Background: Diabetes mellitus (DM) is now one of the most common noncommunicable diseases affecting the global population, with increasing incidence in many emerging countries of the world. 1% reduction in HbA1c is associated with 21% reduction in death related to T2DM, 14% reduction in myocardial infarction and 37% reduction in micro-vascular complications. However, in real practice, poor metabolic control among T2DM is often reported in the literature. Medication non-adherence is of increasing concern for healthcare providers despite the known benefits of modern treatment regimens, with prevalence reported in one study to be in excess of 50 % of diabetic patients. Objective: 1) To evaluate the general level of medication adherence in patients with type 2 diabetes by using
MMAS-8. 2) To identify the correlation between demographic characteristics with medication adherence. 3) To find the associations between medication adherence and glycemic control. Methods: A total of 192 T2DM patients include 82 out-patients and 110 in-patients who was selected at Diabetes Out patient clinical room and admitted to the Endocrinology - Respiratory - Neurology Department, Hue Central Hospital, were evaluated in a Cross-sectional study from January 2015 to April 2017. Morisky scale, also known as Morisky Medication
Adherence Scale (MMAS) was used for the assessment of medication adherence. Results: The average HbA1c was 9.1 ± 2.6%. The proportion of patients having poor glycemic control was 76.0% following HbA1c ≥7.0% criteria and 75.0% following Fasting glucose criteria, and the mean MMAS-8 score was 6.1 ± 1.6 out of a score range of 0-8. There were 51.0% who reported optimal medication adherence (MMA-8 > 6). There are
significant association between demographic variables (living area, occupation, educational level), biochemical marker (HbA1c, fasting glucose, dyslipidemia) with medication adherence following MMAS-8. Higher medication adherence, good control fasting glucose are as statistical predictors of good
glycemic control. Conclusions: Higher medication adherence, good control fasting glucose as statistical predictors of good
glycemic control.