Abstract

Background: Adrenal mass is a relatively rare pathology. Prevalence of adrenal mass are increasing due to an increase in the incidence of adrenal incidentaloma. Clinical manifestations of different symptoms and syndromes depending on localizing adrenal mass and distinguishing between benign and malignant lesions or functional and nonfunctional masses. Objectives: Describe clinical and laboratory features of adrenal mass. Methods: This cross-sectional study is carried out in 51 patients were diagnosed with adrenal mass managed at Hanoi Medical University hospital from July 2018 and October 2020. Results: The study of 51 patients showed that the female/male ratio was 2.4:1, the age of the disease was mainly in the 40-59 age group accounting for 49%. There are 4 patients with Cushing's syndrome, the most common symptoms are hypertension (75%), facial roundness, weight gain around the midsection and upper back, thinning of your arms and legs, easy bruising and stretch marks (50%), low-dose dexamethasone suppression test is not inhibited (100%). There are 13 patients with Conn’s syndrome, the most common symptom being hypertension (69.2%), muscle cramps (30.8%), 100% of patients had an increased aldosterone/renin ratio. There are 4 pheochromocytoma patients with symptoms of hypertension in 100% of patients. The proportion of tumors on the right and on the left is 54.9% and 41.2%, and 3.9% of patients have tumors on both sides. The average diameter on CT/MRI is 28.9 ± 19.9. Conclusions: Clinical symptoms of adrenal mass depend on localizing adrenal mass and distinguishing between benign and malignant lesions or functional and nonfunctional masses.