Abstract

Objective: To predict the risk of coronary artery disease in the next 10 years using the Framingham-2011 scale and related factors in patients with type 2 diabetes mellitus. Methodolgy: A cross-sectional and descriptive study on 270 patients with type 2 diabetes mellitus at Thai Binh Provincial General Hospital. Results: The average risk score for coronary artery disease in the next 10 years according to Framingham-2011 is 13.21 ± 3.68%. The proportion of patients in the moderate-risk group was 53.0%, the high-risk group was 25.5%, and the low-risk group was 21.5%. The mean risk score for coronary artery disease for men (14.04 ± 3.03%) was significantly higher than that of women (12.18 ± 4.15%), (p <0.001). The rate of coronary artery disease in the high-risk group of men (30.7%) was statistically significantly higher than that of women (19.2%), (p <0.01). Whilst Framingham score was inversely correlated with waist circumference (r = -0.144), waist circumference (r = -0,258), and concentration of HDL-C (r = -0.3); it positively correlated with age (r = 0.7), time to detect diabetes (r = 0.46), cholesterol (r = 0.177), blood glucose (r =  0.301),  and  HbA1c  (r  =  0.233)  ).  In  a multivariate model, increased cholesterol levels, decreased HDL-C, increased LDL-C, and increased fasting blood glucose increases the risk of coronary artery disease in the next 10 years. Conclusion: In patients with type 2 diabetes mellitus, the mean risk score for coronary artery disease over the next 10 years according to Framingham-2011 is 13.21 ± 3.68%. The proportion of patients at moderate-risk is 53.0%, and at high-risk is 25.5%. Increased cholesterol levels, decreased HDL-C, increased LDL-C, and increased fasting blood glucose increase the risk of coronary artery disease in the next 10 years.