Abstract

Objectives: 1. Stratification neurocognitive disorder degree of type 2 diabetes by the MMSE and MoCA, 2. The role is screening neurocognitive disorder of MMSE and MoCA and 3. Assessement of common neurocognitive function in type 2 diabetic patients. Method: This prospective pilot study enrolled 102 community dwelling adults with type 2 DM aged 45 years and above. Subjects were assessed using both the MMSE and MoCA. In all subjects, mild neurocognitive and major neurocognitive were ruled out using the DSM 5 criteria, and a functional assessment was done. Sensitivity and specificity analysis, positive and negative predictive values, likelihood ratios and Kappa statistic were calculated. Results and conclusions: - The values average for MMSE score: 25,72± 4,10 and MoCA score: 20,73± 5,08, the average point score of male than female; - The percentage of mild neurocognitive disorder: 41,18% and major neurocognitive disorder: 58,82% (p> 0,247); - Mild neurocognitive disorder group has higher average score than major cognitive disorder group, with MMSE is 27,83±1,87 and 24,23±4,56 (p< 0,0001) respectively; - The values MoCA score in group mild neurocognitive disorder is 24,86±2,62 higher than in group major neurocognitive disorder: 17,83±4,33 (p< 0,0001) respectively; - MoCA score have specificity and sensitivity higher than MMSE score for screening neurocognitive disorder with AUC ROC 92,6% (Se= 80,0%, Sp=92,9 %) compaire to 75,3% (Se=100,00%, Sp= 38,8%), respectively. Cut off MoCA: 21 and MMSE: 23.