Abstract
Turner syndrome is a common chromosomal disorder in females that is caused by the partial or complete absence of one X chromosome or the presence of a structurally abnormal X chromosome. The most constant clinical finding in Turner syndrome is short stature. GH-treatment was suggested to improve growth velocity in children with TS. Objective: To evaluate the effect of GH treatment on growth in children with TS. Subjective: 49 children with TS who were treated with GH for at least 1 year. Method: case series report. Results: 49 children were diagnosed with TS at 8,27 ± 3,43 years and treated with GH at 8,37 ± 3,46 years. The best improvement in height was in the first 3 years of GH treatment 8,37 ± 3,46, 7,55±2,49; 6,51± 2,11 cm, respectively, and the best improvement in the group under 5 years. The weight in children with TS increased steadily over the years of GH treatment, but there was no significant change in BMI. Conclusion: rGH has the best effect on height improvement in the first 3 years of treatment in children with Turner syndrome.