A study on some biochemical profiles of patients with type II diabetes mellitus and cardiovascular disease
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Keywords

blood biochemistry
diabetes
cardiovascular
glomerular filtration rate sinh hóa máu
đái tháo đường
tim mạch
độ lọc cầu thận

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How to Cite

Võ, T. H. H., & Nguyễn, T. K. L. (2024). A study on some biochemical profiles of patients with type II diabetes mellitus and cardiovascular disease. Vietnam Journal of Diabetes and Endocrinology, (62), 122-131. https://doi.org/10.47122/VJDE.2023.62.14

Abstract

The study aims  to  describe  and  find  out about the correlation between some biochemical blood indexes of patients with tuýp 2 diabetes and cardiovascular disease at the same time. Methods: A cross-sectional descriptive study, convenient sampling on 251 patients with tuýp 2 diabetes and cardiovascular disease outpatients at C Hospital in Da Nang. The study variables included: age, sex, serum biochemistry (glucose, urea, creatinine, triglycerides, cholesterol), insulin resistance screened by triglyceride and glucose index (TyG), glomerular filtration rate (eGFR) was calculated using the  creatinine-base  CKD.  EPI formula recommended by the American Society of Nephrology KDIGO and KDOQI. NKF. Results: blood sugar  and  triglycerides of the subjects were quite high, respectively 8.51 ± 3.57 mmol/L and 2.47 ± 1.37 mmol/L, the glomerular filtration rate was quite low 61, 58 ± 18.26 mL/min/1.73m2 of which 50,2% of patients have glomerular filtration rate less than 60 mL/min/1.73m2. There was a statistically significant correlation between glucose, urea, creatinine, triglycerides and cholesterol in male patients. The linear regression model showed that eGFR depends on biochemical indices in the order of blood urea, cholesterol and blood glucose. Conclusions: Routine monitoring of blood biochemical indices can help control complications in patients with concomitant diabetes and cardiovascular disease.

https://doi.org/10.47122/VJDE.2023.62.14
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