Abstract

Non-alcoholic fatty liver disease (NAFLD) is a common condition in patients with type 2 diabetes. This makes blood sugar control more difficult and increase complications in this group of patients. Therefore, early detection of type 2 diabetes patient with NAFLD by simple methods include using FLI index (fatty liver index) and routine liver ultrasound are very important for early intervention in this group of patients. Objectives: To investigate the prevalence of NAFLD by using FLI (fatty liver index) and liver ultrasound in type 2 diabetes patients coming to the national endocrinology hospital for medical examination and find out the relationship between FLI index with some factors: waist circumference, BMI, triglycerides, cholesterol, gammaGT, acid uric, ferritin and several insulin resistance index in the group of diabetic patients with NAFLD. Subjects and methods: A prospective, cross-sectional study including 308 patients from age 30 years and older, diagnosed with type 2 diabetes, examined and treated at the National Hospital of Endocrinology. Results: Based on ultrasound in 308 patients with type 2 diabetes in the study, there were 210 diabetic patients with NAFLD, accounting for 68%, more than the number of diabetic patients without NAFLD (98 patients). In group with FLI>60, which represents patients having a high risk of NAFLD is 101 patients, accounting for 32.8%. The mean value of FLI in patients with type 2 diabetes was 42.3 ± 25.6, in group of diabetic patients with NAFLD was 51.2 ± 25.9. Fatty liver rate by FLI index in patients with type 2 diabetes with NAFLD diagnosed by ultrasound: 40%. The relationship between FLI index and waist circumference, BMI, and triglycerides is a strong positive correlation. The relationship between FLI index and GGT, Total cholesterol, uric acid, ferritin, insulin resistance (HOMA IR) is a slight positive correlation. Conclusion: The rate of NAFLD in patients with type 2 diabetes detected by ultrasound is quite high. The early detection of type 2 diabetes patients with NAFLD by using ultrasound and FLI will seek the early intervention to reduce complications for patients.