Primary hyperaldosteronism due to two ipsilateral adrenal adenomas: clinical case report and review of the literature
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Keywords

Primary aldosteronism
adenoma
hypertension Cường aldosterone nguyên phát
adenoma
tăng huyết áp

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How to Cite

Nguyễn, N. T., & Trần, Q. K. (2024). Primary hyperaldosteronism due to two ipsilateral adrenal adenomas: clinical case report and review of the literature. Vietnam Journal of Diabetes and Endocrinology, (65), 40-46. https://doi.org/10.47122/VJDE.2023.65.6

Abstract

Primary aldosteronism (PA), also known as Conn syndrome, is defined as inappropriate overproduction of aldosterone for sodium status and angiotensin (renin-independent), with three typical characteristics such as hypertension, high aldosterone and low renin. PA is commonly caused by unilateral or bilateral adrenal hyperplasia (65%) and adenoma (27%), almost a solitary adenoma on a side, the prevalence of multiple adenomas in the same gland is very rare. According to literature review, reported from 1977 until now, there have been about 11 rare cases of multiple unilateral adrenal adenomas. In Viet Nam, based on our best knowledge, similar cases have not been reported. Therefore, we would like to present a case of a 48-year-old female patient, admitted to the hospital with reasons of limb weakness, 2- month history of prolonged hypokalemia, and hypertension. After the biochemical results suspected hyperaldosteronism, the patient underwent computed tomography of the abdomen, showed that 2 tumors in the left adrenal gland. Due to lack of experience when approach to this rare case, the patient had suffered laparoscopic resection of adenomas in two different time. Pathology revealed that both tumors were adrenocortical adenomas. After 1 month of surgery, biochemical tests and blood pressure of the patient returned to normal. Thus, in the rare cases of multiple adenomas, physicians need to accurate diagnose and treatment.

https://doi.org/10.47122/VJDE.2023.65.6
pdf (Tiếng Việt)