Risk of bone fractures according to FRAXModel in overweight//obese women over 45 years old
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Keywords

Measure bone mineral density (BMD)
Fracture Risk Assessment Tool (FRAX) model mật độ xương
dự báo nguy cơ

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How to Cite

Lưu, N. G., Lê, A. T., & Nguyễn, H. T. (2021). Risk of bone fractures according to FRAXModel in overweight//obese women over 45 years old. Vietnam Journal of Diabetes and Endocrinology, (37), 44-52. https://doi.org/10.47122/vjde.2019.37.5

Abstract

Objectives: To investigate the risk  of bone fractures in overweight/Obese women. Subjects and research methods: 207 women in 2 groups (1) 147 overweight/obese (BMI ≥ 23kg /  m2) and (2) 60 is  normalweight (BMI<23kg / m2). Measure bone mineral density (BMD) by DEXA method and assess fracture risk according to Fracture Risk Assessment Tool (FRAX) model. Results: BMD in the overweight/Obese group is higher than the normal group  (0.64  ±  0.11 compared to 0.60 ± 0.12), p <0.05. - The prevalence of osteoporosis and osteopenia in the femoral neck (FN) of overweight/obese group is 27.9% and 50.3%, respectively, the normal group is 45.0% and 43.3%. - The rate of osteoporosis and osteopenia in the lumbar spine (LS) of the overweight/Obese group is 45.6% and 34.7%, respectively, the normal group is 48.3% and 43.4% .- The rate of osteoporosis in the overweight/Obese  group is low than the normal group by assessing the T  index   in  the  FN  (27.9%  and  45.0%),  p<0.05. Predict the risk of bone fractures according to FRAX.- The probability of total fracture in 10 years ≥ 20% accounts for 1% and the probability of femoral neck fracture in 10 years ≥ 3% accounts for 20.3%. - The rate of general osteoporosis in FN is 32.9% and the rate indicated for Osteoporosis treatment is recommended by NOF is 45%. Conclusions: The bone density of overweight/obese women is not reduced but still at risk of bone fractures.

https://doi.org/10.47122/vjde.2019.37.5
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