Evaluation of dyslipidemia and atherogenic index in the newly diagnosed prediabetic subjects in Quang Binh province

Từ khóa

Prediabetes
Lipid Profile
Atherosclerotic index Tiền đái tháo đường
chỉ số lipid
chỉ số xơ vữa động mạch

Ngôn ngữ sử dụng

Cách trích dẫn

Le, V. H., Nguyen, H. T., Tran, H. D., & Nguyen Hai, N. M. (2023). Evaluation of dyslipidemia and atherogenic index in the newly diagnosed prediabetic subjects in Quang Binh province. Vietnam Journal of Diabetes and Endocrinology, (53), 5-11. https://doi.org/10.47122/vjde.2022.53.1

Tóm tắt

Dyslipidemia is associated with  an increased risk of cardiovascular disease. Vascular complications emerge even in pre- diabetes [3]. Many studies have found that dyslipidemia commonly precedes the onset of type 2 diabetes and that this disorder resembles insulin resistance syndrome. Objectives: 1. Determine the rate of newly diagnosed prediabetes in the community in Quang Binh province; 2. Evaluate the dyslipidemia and atherogenic index in the newly diagnosed prediabetes . Methods: A cross-sectional and descriptive design. Employing a two-stage cluster sampling method, we recruited non- diabetic/pre-diabetic adults (ages range from 20 - 60 years) from Quang Binh province. Prediabetes and dyslipidemia were defined according to  international   Results: Newly diagnosed prediabetes was detected in 35% of participants, and diabetes was 14.8% (p = 0.01) in 1206 study subjects. In the prediabetes group, there were 27.5% with high TC, 41.7% with high TG, 37.9% with high LDL-C levels, 41.8% with low HDL-C levels, and 47.5% high non-HDL-C levels. 9.6% of participants with prediabetes had a ratio of TG/HDL-C with the risk value, LDL-C/HDL-C (57.8%),   and   TC/HDL-C   (41.4%).  HbA1C level is significantly associated with HDL-C, non-HDL-C,       TG,       and       LDL-C/HDL-C. Conclusion: Prevalence of prediabetes very high in population at Quang Binh Province. The dyslipidemia (high TG and low HDL-C levels) and abnormal atherogenic index (high Non HDL.C, high TC/HDL.C and high LDL.C/HDL.C) are also risk factors for prediabetic subjects in Central Vietnam .

https://doi.org/10.47122/vjde.2022.53.1