Abstract
Introduction: Survey on insulin resistance in patient with nonalcoholic fatty liver disease. Subject and method: A total of 40 examined patients in Bachmai hospital Consultation Center with Nonalcoholic Fatty Liver Disease (NAFLD) were enroll in this cross sectional study from February 2020 to July 2020. Result: In this cross sectional study, the prevalence of insulin resistance was 77.5% in NAFLD subjects, the increased risk of insulin resistance was associated with NAFLD classification (class 1, 2, 3 is 3.89 ± 2.43; 4.68 ± 2.97; 6.66 ± 1.99, respectively), the result had statistically significant (P < 0.05). The risk of insulin resistance was significant higher in group with clinical features such as NAFLD Class 2,3, obesity, overweight, and also surge in group whom paraclinical tests results showed abnormality such as impaired fasting glucose, dyslipidemia (high total cholesterol level, high triglyceride level, low HDL cholesterol level), and elevated liver enzymes. There were moderate correlation coefficients between HOMA-IR with classification of NAFLD, BMI, cholesterol level, and triglyceride level. Nevertheless, HOMA-IR and fasting blood glucose had a strong curvilinear relationship.