Observation of hypercoagulable factors based on D-dimer, fibrinogen and hyperglycemia in hospitalized diabetic patients infected with COVID-19
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Keywords

Đái tháo đường
COVID-19
tăng đông
D-dimer
Fibrinogen Diabetes
COVID-19
hypercoagulability
D-dimer
Fibrinogen

Working Languages

How to Cite

Lâm, Ái Q., Huỳnh, L. T. B., Trần, T. N., & Lâm, V. H. (2024). Observation of hypercoagulable factors based on D-dimer, fibrinogen and hyperglycemia in hospitalized diabetic patients infected with COVID-19. Vietnam Journal of Diabetes and Endocrinology, (65), 19-24. https://doi.org/10.47122/VJDE.2023.65.3

Abstract

Background: COVID-19 is one of the fatal respiratory diseases due to many mechanisms, including the mechanism of hypercoagulability, which leads to arterial occlusion, pulmonary infarction, and cerebral infarction. Diabetes makes COVID-19 infection more severe. Diabetic patients infected with COVID-19 are at high risk for serious complications and need to be monitored and treated promptly. Objectives: 1) Survey clinical characteristics and blood glucose in diabetic patients infected with COVID-19. 2) Survey on hypercoagulability in diabetic patients infected with COVID-19 and related factors. Methods: A crosssectional descriptive study on 86 diabetic patients with COVID-19 treated at the COVID-19 Intensive Care Center - Hue Central Hospital in Ho Chi Minh City from August 2021 to November 2019. Results: The average age of the study subjects was 61.98±12.91 years old, 47.7% male and 52.3% female. Regarding the glycemic index, the average glucose concentration was 19.7 mmol/L and HbA1c was 8.3%. Regarding hematological indicators, the average concentration of D-Dimer was 3031.8 mg/L and Fibrinogen 4.5 g/L. Conclusion: There is increased coagulation in diabetic patients infected with COVID-19 manifested by two D-Dimer and Fibrinogen index. At the same time, there was an inverse correlation between SPO2 concentration and D-Dimer concentration with statistical significance (p<0.05).

https://doi.org/10.47122/VJDE.2023.65.3
pdf (Tiếng Việt)