Abstract
Objective: To determine the correlation between serum PTH and some factors related to chronic kidney damage in type 2 diabetes patients with chronic kidney disease. Methods: the study subjects included 123 type 2 diabetes participants who had not Kidney replacement therapy, with eGFR <60 ml/minute and urine albumin positive or negative. Study subjects were quantified for PTH as well as variables related to chronic kidney damage such as blood pressure, serum urea, creatinine, total calcium, phosphorus, eGFR and hemoglobin levels. We determined the correlation between serum PTH and these variables. Results: There was a negative correlation between serum PTH and hemoglobin, total calcium, eGFR with correlation coefficients of 1= -0.27, p=0.002, 1=-0.44 (p< 0.001); 1=-0.594 (p<0.001). respectively. There was a positive correlation between serum PTH and systolic blood pressure, serum phosphorus, urea, creatinine with correlation coefficients of 1=0.18 (p=0.046);
1=0.43 (P<0.001); 1=0.61 (P<0.001); 1=0.689 (p< 0.001), respectively. Conclusion: There is a close relationship between PTH levels and serum calcium, phosphorus, estimated glomerular filtration rate.