Abstract

Coronavirus disease 2019 (COVID-19), the viral illness caused by the novel coronavirus SARS-CoV-2. COVID-19 is now recognized as a multi-organ disease with a broad spectrum of manifestations. Similarly to post-acute viral syndromes described in survivors of other virulent coronavirus epidemics, most patients with COVID-19 get better within weeks of illness, but there are increasing reports of persistent and prolonged effects after acute COVID-19 in some patients. The post-acute COVID syndrome may also be known as Post Covid conditions, long COVID, long-haul COVID, long-term effects of COVID or chronic COVID. Post-acute  COVID syndrome are a wide range of new, returning, or ongoing health problems people can experience four or more weeks after first being infected with the virus that causes COVID-19. Even people who did not have COVID-19 symptoms in the days or weeks after they were infected can have post-acute COVID syndrome. The prognosis of this new clinical entity is not known and is likely dependent on the severity of clinical symptoms, underlying comorbid conditions, and response to treatment. More clinical studies evaluating patients with post-acute COVID-19 syndrome, are required to understand the duration and the long-term effects of this new clinical entity. Given the global scale of this pandemic, it is apparent that the healthcare needs for patients with sequelae of COVID-19 will continue to increase for the foreseeable future. Rising to this challenge will require harnessing of existing outpatient infrastructure, the development of scalable healthcare models and integration across disciplines for improved mental and physical health of patients with Post acute COVID-19 syndrome in the long term.