Tóm tắt
Objectives: To evaluate some of clinical characteristics and glutamic acid decarboxylase (GAD) antibody in non-overweight, obese diabetic individuals. Methods: A cross-sectional study on 284 non overweight- obesity diabetic patients at Hue Central hospitap from August, 2017 to August, 2019. All patients were measured autoantibodies glutamic acid decarboxylase (anti-GAD). GAD antibody-positive was determined when autoantibodies to GAD concentration was higher than 5 IU/mL. Clinical data (age, sex, weight, hight) were obtained. Data were analysed by SPSS version 16.0. Results: In non overweight- obesity diabetic patients with GAD antibody- positive, the average age was 60.27 ± 16.57 year, lower than in GAD antibody-negative patients group (66.86 ±14.32 year), p<0.05. In GAD-antibody positive patients group, women accounted for 40.91% and men accounted for 59.09%. The percentage of GAD-antibody positive in patients aged 35 years and older were distributed as follows: aged 40 and younger:16.67%; ages 40 to 59: 11.11%; ages 60 to 74: 7.44%; and aged 75 and older: 4.4%; Conclusions: In non overweight-obesity diabetic patients, GAD-antibody positive condition is descending with age.