Abstract
Objectives: To investigate plasma thiamine level and rates of its changes in patients with type 2 diabetes mellitus (T2DM patients). Subjects and methods: 254 participants divided into 2 groups including 161 T2DM patients in the study group and 93 individuals in the control group were measured plasma thiamin level by ELISA method. Results: Thiamine level in T2DM patients was significantly lower than that in the control group. The rate of patients with thiamin reduction was 86.3%. Thiamin level and decreased thiamin rate were similar between male and female patients, between age groups. Conclusions: Plasma thiamin level was decreased in T2DM patients. Patients with reduced thiamin level was seen with a high rate. There were no significant differences in thiamine levels between men and women as well as between age groups.