Abstract

Coronavirus disease 2019 (COVID-19) has completely changed our daily clinical practice as well as our social relations. Many organs and biological systems are involved in Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection and endocrine system is not only an exception. Vaccination is one of the most effective ways to protect patients against COVID-19. Evidence indicates that vaccines are very effective at preventing severe illness, hospitalization and death from COVID-19. Since the first outbreak of COVID-19, ongoing efforts have been made to discover an efficacious vaccine against COVID-19 to combat the pandemic. The clinical course of COVID-19 and the effects of vaccination against COVID-19 are both influenced by patients’ health status and involve a systemic physiological response. In view of the systemic function of endocrine hormones, endocrine disorders themselves and the therapeutics used to treat them can influence the outcomes of vaccination for COVID-19. However, there are very limited data to support the development of clinical guidelines for patients with specific medical backgrounds based on large clinical trials. In the current severe circumstances of the COVID-19 pandemic, position statements made by clinical specialists are essential to provide appropriate recommendations based on both medical evidence and clinical experiences. As endocrinologists, we would like to present the medical background of COVID-19 vaccination, as well as precautions to prevent the side effects of COVID-19 vaccination in diabetic and endocrine patients including autoimmune thyroid disease, osteoporosis, adrenal insufficiency, hypogonadism, and pituitary disorders. We should be aware of the priority and benefits of COVID-19 vaccines in Diabetic and Endocrine Patients and recommend prompt vaccination to patients.